Real coach Zinedine Zidane left out Cristiano Ronaldo and Gareth Bale in a largely second-string side but not even the injection of youth could breathe life into his team until Asensio's late goal ended a run of three games without a win.
The teams finished level at 3-3 on aggregate in the tie but the Lisbon club advanced to the quarter-finals after Adan kept out Martinelli's weak effort.
IMAGES from the soccer matches played across leagues on Friday
IMAGES from La Liga matches played on Sunday
Barca's second-half stamina key to their massive lead in the standings this season
Bayern Munich eased past title rivals Borussia Dortmund 3-1 on Saturday to secure their 10th consecutive Bundesliga crown in front of a sold-out home crowd and with three games to spare, while Paris St Germain secured a record-equalling 10th French top flight title after stuttering to a 1-1 home draw by 10-man RC Lens.
Real Betis right-back Emerson Aparecido's first year in La Liga went superbly well, but there is plenty to come from one of the league's most talented and determined rising stars.
Zinedine Zidane's side joined Atletico Madrid on 66 points and moved top of the table
Barcelona blew the La Liga title race wide open when Lionel Messi scored a hat-trick in a 4-3 comeback win for the champions at 10-man Real Madrid in an action-packed 'Clasico' on Sunday.
With football matches cancelled across Europe to stop the spread of the coronavirus, La Liga players Borja Iglesias and Sergio Reguilon found a novel way to attract 60,000 online fans - by battling out a thrilling Seville derby on the FIFA 20 videogame. Fans in Andalusia suffering from La Liga withdrawal symptoms after Sunday's clash between Sevilla and Real Betis was postponed tuned in for the showdown between Betis's Iglesias and Sevilla's Reguilon on streaming service Twitch.
Colombian super-sub Jhon Duran scored two late goals as Aston Villa salvaged a 3-3 home draw with Liverpool.
Spanish soccer's 'El Clasico' encounters between Barcelona and Real Madrid will happen in December and April, two of the most anticipated games of the 2016-17 Primera Division season whose fixtures were announced on Friday. Defending champions Barca host Real on Dec. 4 at the Camp Nou. The reverse fixture will take place on April 23, at the Bernabeu stadium, the Spanish Football Federation (RFEF) confirmed after the draw. As the La Liga season kicks off, Barca will begin their title defence at home to Real Betis on Aug. 21.
Here are five talking points from the weekend's action:
'But he was very quick and did a very stylish adab.' 'Of course, I didn't expect him to hug.'
A summary of Saturday's action in the Bundesliga and La Liga.
Ballon d'Or winner Cristiano Ronaldo scored the opening goal as 10-man Real Madrid beat Osasuna 2-0 on Wednesday to qualify for the King's Cup quarter-finals 4-0 on aggregate.
Karim Benzema gave the European champions the lead in the 20th minute with an irresistible piece of control and finish after a pinpoint pass from Luka Modric.
La Liga leaders Barcelona moved 10 points clear with a 4-1 win at Real Betis on Sunday after second place Atletico Madrid slipped up at Athletic Bilbao on Saturday in a 2-0 defeat.
Unbeaten in six games, the draw leaves third-placed Sevilla on 51 points, four ahead of Real Sociedad and five ahead of both Getafe and Atletico Madrid, while Levante are 12th on 35 points.
Valencia, who lifted the trophy on their last appearance in the showpiece match in 2008, will meet 30-times winners Barca in the final on May 25 at Betis' Benito Villamarin stadium.
Real Madrid coach Zinedine Zidane denied his side were facing a crisis after they drew 1-1 at home to La Liga minnows Eibar and racked up a fourth consecutive draw for the first time in more than 10 years.
Luis Suarez grabbed a hat-trick and Lionel Messi bagged two goals as Barcelona began their quest for a third straight La Liga title with a 6-2 rout of Real Betis on Saturday. Arda Turan, whose two goals against Sevilla helped Barca lift the Spanish Super Cup on Wednesday, gave them an early lead at the Nou Camp before Ruben Castro equalised in the 21st minute. Barca went back in front thanks to a trademark 37th-minute goal from Messi before Suarez, La Liga's top scorer last season, made it 3-1 before halftime.
"According to the report issued from the city hall in Vigo, they consider that the Balaidos stadium is not safe for spectators or for players to attend the game on Sunday," said a statement from La Liga.
Real play Athletic Bilbao while Barcelona visit Real Sociedad in fixtures that have often proved to be among their hardest away trips over the last decade.
Barcelona fell to a first home defeat in any competition for more than two years
Girona reclaimed top spot in LaLiga after beating champions Barcelona 4-2
IMAGES from the Europa League matches played on Thursday.
Manchester United manager Erik ten Hag backed Bruno Fernandes to continue his role as stand-in skipper.
Neymar stole the show from the likes of Lionel Messi, Cristiano Ronaldo and Gareth Bale when the Brazilian's strike set Barcelona on the way to a 2-1 win over Real Madrid in Saturday's 'Clasico' at the Nou Camp.
Barcelona finished three points behind Real Madrid last season but there is concern the gap between Spain's biggest two sides could be far larger this season.
The season kick backs into action with a local derby between Sevilla and Real Betis on June 11 and there will be fixtures for the following seven days, with Barca hosting Leganes on June 16
Real Madrid closed to within three points of La Liga leaders Barcelona and Atletico Madrid at the halfway stage of the season when a Pepe header secured a laboured 1-0 win at mid-table Espanyol on Sunday.
No Dutch top-flight league soccer title will be awarded this season after the COVID-19 pandemic brought the campaign to a premature close, the Dutch FA (KNVB) said after a meeting with clubs and unions representing coaches and players on Friday. Ajax were top of the Eredivisie table with 56 points from 25 games, only ahead of AZ on goal difference, and both teams will now fill the Netherlands' qualifying places in UEFA's 2020-21 Champions League, Europe's elite club competition.
Cristiano Ronaldo shrugged off the boos of his own supporters to fire Real Madrid to a 3-0 win over Real Sociedad on Sunday.
Zinedine Zidane has said his side are in a delicate situation as they prepare to host arch-rivals Barcelona in a La Liga title showdown on Sunday
Atletico Madrid kept pace with leaders Barcelona and restored their five-point lead over third-placed city rivals Real when Diego Costa and David Villa each scored a penalty in a 2-1 win at Granada in La Liga on Thursday.
News of all that's transpired on and off the football field.
Barcelona midfielder Ivan Rakitic embraced the art of winning ugly after they beat 10-man Real Betis 2-0 to move closer to retaining their La Liga title.
Manchester City squandered a three-goal lead to draw 3-3 with Feyenoord in the Champions League on Tuesday.
The 55-year-old Ernesto Valverde, who led Barcelona to successive La Liga titles in 2018 and 2019, came under fire this season for the team's dip in performance levels even though they top the league standings at the halfway point of the campaign.